: 5-FU is associated
possible side effects which can be quite severe. During the treatment, cancer patients tend to experience a loss of
appetite, diarrhea, nausea and vomiting, and dehydration problems. More serious adverse effects can include severe
diarrhea, pain or cramping in the abdominal area, or blood in the stool. These complications require immediate
Indication: 5-FU is a medication that is often
prescribed for people who have topical cancer on their upper layer of skin. These kinds of cancer are sometimes referred to as non-melanoma cancer or
actinic keratoses. The medication is gently rubbed on the affected
skin areas. It attacks the abnormal cells that are quickly growing,
which is the main characteristic of cancer cells. It should not
affect the non-cancerous cells, but the cancerous cells that are located in the top layer of the
skin. There has also been some effectiveness with some cancers in
the eye after other treatments have been shown ineffective in helping them.
the side effects mimic the appearance of an infection because 5-FU is attacking and killing the quickly growing
cells. You may experience redness of the skin and the affected area
may swell. Often, a tingling or burning sensation causes some
discomfort and oozing can also occur. Changes to the color of the
skin are also quite common. It is best to limit exposure to the sun
as the skin is often highly sensitive when a person is using this medication.
As with any medication, 5-FU should
be used only under the supervision of a physician. However, the
general dosage is usually one or two times each day and this can continue for a few weeks. The medicine may come as a lotion or other liquid solution or even a
cream. When you apply it to your skin, do not use
metal. You may use gloved hands or bare hands, but if you use
your bare hands it is important to wash your hands thoroughly with soap and warm water to remove all traces
also important that you do not apply dressings or bandages unless your medical professional has specifically
asked you to do so. Your physician will prescribe a specific dosage
and you should follow his instructions carefully and check back at the appointed times to make sure that the
cancerous cells are all gone.
Overdose: the fact
that 5-FU is a
tropical treatment, the risk of overdose is a little difficult. However, the medication may cause
irritation and/or inflammation even at normal. If irritation is such that you cannot continue the treatment,
contact your health care provider before taking any decision.
is important that you use 5-FU exactly as indicated by your physician or pharmacist; in case you forgot to apply
the medication, apply the missed dose as soon as you remember it; if it is almost time for the next dose, skip
the missed dose and continue your regular dosing. Double dose is not recommended.
Store 5-FU at room temperature and out of reach of children. The drug should not be kept in the light or moisture.
After use, do not throw the container in the garbage. For more information on proper disposal of 5-FU, talk to your
physician or pharmacist.
It is possible that other medications that are used directly on
the skin could interact with 5-FU, so it is important to discuss all of your medications, both topical and oral,
with your physician before starting this course of treatment.
Specific contraindications are not currently listed for 5-FU, but it is always necessary to talk with your
medical professional about your current state of health before you start using this topical cream or any
Side effects: in some patients, 5-FU can cause
skin reactions. Common 5-FU side effects include:
If the side
effects above persist for days or weeks, contact your oncologist. In addition, contact your doctor immediately
if you experience any of these symptoms:
severe red skin rash