Warning: Arimidex has been
linked to cardiovascular risk in women with preexisting ischemic heart disease (IHD). The
medication may cause fetal harm when administered to a pregnant woman. The drug should not be taken by
premenopausal women with breast cancer as it offers no clinical benefits, according to the FDA.
Arimidex is used for the treatment of breast cancer. It is intended
for women who have breast cancer and are postmenopausal. This
drug is prescribed to help slow or stop the growth of cancer cells.
Because many cancer tumors need estrogen to grow this medication purpose is to lower estrogen levels in the
blood. For women that have not had success using tamoxifen, this drug
may be used. Arimidex comes in tablet form to be taken by mouth, with or without
Arimidex should only be taken as
indicated on your prescription label. If you do not understand
or are confused by any of the directions, ask your doctor or pharmacist for an explanation. This medication is intended to be taken by mouth and comes in tablet
form. The usual dosage is one tablet once a day and can be taken
with or without food. If you notice your stomach is upset when your take your medication on an empty stomach
then eat something. This medication should be taken at same time
every day. Take only as directed. Take the dosage your doctor prescribes, do not increase or decrease on your
drug can be taken for several years if needed. Just because you
feel well you should not stop taking your medication without talking with your doctor first.
Along with your
prescription your pharmacist may provide a copy of the manufacturer’s information for patients. Consider taking some time to read this information.
Note that although cancer patients can take the
medication with or without food, it is better to take Arimidex after a meal to reduce the risk of nausea or
is in pill form, overdose can occur during the treatment. In case you experience overdose symptoms, contact your
doctor or a local poison control center near you immediately. They will do what is necessary to eliminate or reduce
the symptoms, and avoid serious complications.
Missing dose: If you you forget to take
Arimidex at the
recommended time, take the missed dose as soon as you remember it if it is not almost time for the nest dose. In
case it is time for the next dose, do not double it to recover the missing, it can be dangerous. Contact your
doctor or wait to go back to your regular schedule.
You may be asked to take a pregnancy text before this drug is prescribed as using Arimidex while you are
pregnant could harm your unborn baby. Do not take this drug if you are allergic to Arimidex. You should also not take this drug if you are breast feeding, or if you have
not completed menopause. This drug is not used for men or children.
your doctor if you have heart disease, circulation problems, or high cholesterol. If you have a history of blood clots or strokes, osteoporosis, severe liver
disease, or low bone mineral density, your doctor should know.
Mechanism of Action
Arimidex works by
inactivating the action of aromatase, an enzyme necessary for the conversion of androgen into estrogen. Once
deactivated, aromatase is unable to provide estrogen to the growth and survival of breast cancer cells.
Interactions:Your doctor is likely already aware of a potential
drug interaction. Do not stop taking any medication without
speaking to your doctor first.But be aware that very serious interactions may occur with estrogens or
tamoxifen. Let your doctor know if you are taking estrogens or
tamoxifen and have not started taking Arimidex. Any nonprescription
or herbal remedy or vitamin supplements you are using should be disclosed to your
doctor as well. Be sure to let your doctor and
pharmacist know all of the medication you are taking. These may not
be the only drug interactions.
Do not take
Arimidex with the following
Side effects: while
this medication can help certain women to fight their breast cancer, it may cause some
adverse effects in most patients. Fortunately, these adverse effects tend to disappear when the body adjusts to the
medication. The most common
Arimidex side effects include:
- persistent or frequent need to
hair thinning or hair loss
stomach pain and heartburn
- difficulty falling or staying
nausea and vomiting
bowel disorders – constipation or diarrhea
joint, bone, or muscle pain
mood changes or/and depression
Feeling of burning or tingling in your hands or feet
rare, Anastrozole can cause
serious side effects which require immediate medical attention; contact your doctor immediately if you
experience any of these symptoms:
shortness of breath
difficulty swallowing or breathing
yellowing of the skin or eyes (Jaundice)
Skin problems: ulcers, itching, rash, blisters, hives, etc.
vaginal problems such as bleeding, dryness or irritation
fever which can be accompanied with
sore throat and cough
Swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower