Warning: Carboplatin can cause various serious side effects that can
seriously affect the health of a patient who is using it. When the medication is used over an extended period of
time, it can cause certain blood disorders such as anemia and blood marrow suppression, which may result in
infections or bleeding problems. The risk continues to increase with prolonged use and higher dosages.
Traditionally, doctors will order various tests in order to monitor the number of blood cells in bone marrow so
that any changes will be evident.
also a slight possibility of allergic reaction with this medication. Although uncommon, this reaction usually
occurs within a few minutes of receiving the medication. All of the following side effects merit consultation
with a medical professional: evidence of infection (fever, persistent sore throat), easy bruising/bleeding,
unusual tiredness, rash, itching, swelling, severe dizziness, difficulty breathing.
Carboplatin is a drug that is in liquid form and is in a class of drugs that are defined by the fact that they
contain platinum. It is often used as part of chemotherapy treatment and can be administered alone or along with
various other medications. It works to slow or to completely stop the reproduction of cancer cells in the body. One
of the brand names for this medication is Paraplatin.
drug is often used in the treatment of several types of cancer which include (but are not limited to) ovarian
cancer, testicular cancer, cancer that affects the head and neck, bladder cancer, Wilms’ tumor, tumors in the
brain, and retinoblastoma.
Like other medications that
are used in chemotherapy, Carboplatin is generally administered and overseen by a medical professional. The
intravenous injection usually takes at least fifteen minutes.
The dosage of this drug can vary from person to person and is affected by body type and size, as well as by the
severity and the variety of the specific medical condition. While the amount given in a single dose may vary, it is
not usually done more than once in a four week period, although this will be decided by the doctor
Overdose: the fact that
Carboplatin is administered in hospital, the risk of overdose is greatly reduced; however, it is not impossible.
Carboplatin overdose increased the toxic effects of the medication, and cause severe headaches, malaise or life
threatening conditions. If you suspect that you are overdosed, contact your health care provider or visit a
drug and poison center
near immediately. Any negligence in chemotherapy overdose can lead to death.
If you have a blood marrow
or blood cell disorder, kidney problems or a mineral imbalance, consult with your doctor before taking this
medication. In addition, carboplatin
is not indicated for patients who fall in the following conditions:
who are breastfeeding
to carboplatin or its ingredients
of severe allergy to mannitol.
There are several different medications that may interact with this drug in a variety of ways. That is why it is
essential that you maintain a comprehensive list of the medications that you are taking and that you fully
disclose this list to the doctor or pharmacist. Some of the medications that may interact with Carboplatin are
amphotericin B, aminoglycoside antibiotics, certain diuretics, certain anti-seizure medications, and nalidixic
effects: In addition
to stopping the growth of cancer cells, Carboplatin may also interfere with your healthy cells that multiply
quickly, and cause adverse effects. Common Carboplatin side effects include:
- hair loss
ear ringing or
- decreased appetite
numbness or tingling in the fingertips
disorders (constipation or diarrhea)
- Formation of sores in the
rare, Carboplatine can cause serious side effects which require immediate medical attention; contact your doctor
immediately if you experience any of these symptoms:
(temporary loss of
- shortness of breath or
- high blood pressure
- painful or difficulty
- yellowing of the skin
or eyes (jaundice)
bruising or bleeding
- skin disorders such as
rash, hives or itching
- Swelling of your arms,
feet, ankles, or lower legs.
1 - nlm.nih.gov, Carboplatin