Warnings: There are possible serious kidney problems and serious
allergic reactions possible while using Cisplatin. Hearing loss (more common in children), bone marrow suppression,
severe nausea and vomiting and bleeding problems may occur with this medication. The chances of these side effects
increase with the dosage you are taking.
your doctor about any of these symptoms: trouble breathing, changes in the amount of your urine, swelling of the
face, rashes, dizziness, ringing in the ears, easy bruising and bleeding, signs of infection, vomiting or
nausea, unusual tired or weakness.
Indications: Cisplatin is a chemotherapy composed
of platinum for the treatment of various types of cancer. It is meant to slow or stop the growth of certain
types of cancer.
used, most of the
times, in association with other anticancer drugs, to treat the following
- multiple myeloma
- testicular cancer
- ovarian cancer
- bladder cancer
and neck cancer
- esophageal cancer
- small cell
small cell lung
- cervical cancer
- stomach cancer
- Prostate cancer
- Hodgkin's lymphoma
This medication is
intravenously given by a medical professional to the patient. The dosage that is given will depend on your body
size, height and response to therapy. This medication should not be given more than once every 3 to 4
doctor should intravenously give you more fluids while you are receiving this treatment. You should intake more
fluids to reduce the risk of side effects from your kidneys. If you have any contact with the treatment,
immediately wash your hands with soap and water.
Tell your doctor about any allergies you have, including to carboplatin which may make you have an allergic
reaction. You should also tell your doctor if you have decreased bone marrow function, kidney disease, and loss
of hearing and blood cell disorders. Tell your doctor all of your medical history including, numbing and
tingling of the feet and hands, mineral imbalance, gout and kidney stones.
should consult your doctor before receiving any immunizations. Avoid people that have had recent oral polio
vaccinations. Elderly people and children are more susceptible to the side effects, including hearing loss,
tingling of the hands and feet and bleeding problems. Children are more susceptible to hearing loss than most.
women should not take this treatment as it can cause serious birth defects. It is known to pass through breast
milk so women that have children should not breastfeed. Males also have their sperm affected by this medication
so they should use birth control.
There are some medications that will interact with Cisplatin and cause harmful side effects. Amphotericin B,
anti-seizure medications, aminoglycoside antibiotics, “water pills” (loop diuretics such as furosemide,
bumetanide, ethacrynic acid), nalidixic acid pyridoxine when used in combination with both altretamine and
Cisplatin can all have very harmful interactions. Consult with your doctor about all medications that you are
In addition to cancer cells, cisplatin also damage normal cells, which causes various side effects in most
patients. The most common cisplatin side effects include:
- hair loss
- weight loss
- diarrhea or
- nausea and
- changes in
- Numbness or tingling
in the fingertips and toes.
Cisplatin can cause
serious side effects which require immediate medical attention; contact your doctor immediately if you
experience any of these symptoms:
- severe depression
- shortness of
- unusual bruising or
- dizziness or/and
- pain in your side or
- Swelling of your feet
ch.oddb.org, Information professionelle sur Cisplatin-Teva®
2 - nlm.nih.gov,