: There are several precautions to be aware of before you begin taking Fludara. There are some potentially harmful
side effects, so you should consult your doctor’s office if you experience any of them.
One of the main precautions is the potential to experience blood or bone marrow disorders. Some of the ways you
will know if you have one of these problems is whether you bleed or bruise more easily than usual, or both, and if
the bleeding or bruising does not heal easily. Another symptom of having a blood or bone marrow problem is if you
are more sensitive to infections. You may experience chills, or a fever, or a persistent sore throat; so contact
your doctor if you have any of these side effects.
It is also important to know whether or not you have an allergy to this medicine. If you have taken it before or
had an allergic reaction to the drug, let your doctor know right away.
Fludara is used
primarily to treat certain kinds of cancers by slowing or stopping the continued growth of harmful cancer
medication is mainly used to treat the following medical conditions:
- chronic lymphocytic leukemia (CLL), in patients for whom other forms of treatment
have not worked
- Indolent or
low-grade non-Hodgkin's lymphomas in
patients that have been unsuccessfully treated with other forms of treatment.
Fludara may only be prescribed and administered by a physician or other health care professional. Your doctor will
decide on your appropriate dose amounts and schedule for receiving the medicine based on your general
health, whether you are taking other chemotherapy drugs or not, the severity of the tumor and your body mass
This drug comes as a
powder to be added to a medical fluid and injected intravenously. Usually, the appropriate dose is taken once daily
for five consecutive days, every 28 days. The injection takes about 30 minutes to be over. Appropriate
administering is crucial. Fludara can damage organs in your body.
It is very important during the treatment that you drink plenty of water to help your body get rid of the toxic
effects of the drug. This helps prevent kidney problems and improve the curative effects of the
overdosing any chemotherapy drug can be fetal. Fludara overdose can be dangerous. Even at normal dose, Fludara can
lead to a decrease in white blood cells and platelets, which can cause serious infections; therefore, avoid
anything that might weaken your immune system and the risk of infection while taking
The medication can also damage your nervous system, and lead to seizures, restlessness, and even coma. In some
patients, Fludara can cause lung damage, and other unpredictable life threatening health problems. During the
treatment, respect all appointments you have with your doctor. If you think you have taken an overdose, contact
your doctor or the poison control center nearest you as soon as possible.
is basically difficult to miss a dose of Fludara if you are present for your appointment. Do not neglect your
appointment; one missed dose of Fludara can
affect the entire treatment. If for some reasons you cannot be present at the hospital for the treatment,
contact your health care provider. Do not stay home because you are experience side effects; Fludara cause
adverse effects in most patients.
: Some contraindicative situations may arise if you are already experiencing certain medical conditions that can
become worse once your take this prescription. If you have had infections in the past, or certain kinds of viruses,
then let your physician know before taking Fludara. This drug can also worsen problems associated with blood
disorders, such as lack of blood clotting or anemia. Talk to your physician about your medical history and about
all possible warnings and side effects of this medication.
Fludara is not recommended in the following conditions :
to Fludara or any of its constituents
with live attenuated vaccine
not recommended or should be used with caution in patients whose general condition is poor, mainly those
- Opportunistic infections.
: Unfavorable drug interactions occur when you are taking more than one medication at once and they influence each
other. You may be taking one or more medications in addition to this drug. Some medications are acceptable to take
at the same time; some are not. Some medicines that are not recommended to be used at the same time as this
medication are: live vaccines like the flu vaccine, salicylates such
aspirin or ibuprofen, and blood thinners like enoxaparin and warfarin. Give your doctor a complete list of all of
your medications so that the doctor can tell you which medicines are okay to continue taking or can recommend
replacements. You should not try to manage your own medicine routine as this can cause
Contact your doctor before using the following medications:
Fludara tends to cause these following side effects:
nausea and vomiting
rash or itching
Tiredness or weakness
If the side
effects above persist for weeks, contact your oncologist. In addition, see your doctor if you experience any of
pain or discomfort
- fast or
- yellowing of the skin
of the arms, hands, feet, ankles, or lower legs
pain or tingling in the hands, arms, feet, or legs.
nlm.nih.gov, Fludarabine Injection