Warning: Rare but very serious side effects are associated with Nolvadex including strokes,
blood clots in the lungs/legs and uterine cancer. If you are taking this medication to reduce the risk of breast
cancer, discuss with your doctor the benefits and risks of taking this medicine. If you are taking this medication to treat breast cancer, the benefits greatly
outweigh the risks of side effects. If you develop symptoms of a stroke or blood clots such as chest pain, weakness
on one side of the body, slurred speech, calf pain and swelling or sudden changes in vision, call a doctor or go to
a hospital immediately. It’s also important to notify a doctor or health care professional if you experience
changes in your monthly menstrual period or have unusual vaginal discharge or pain in your lower stomach. These may
be signs of cancer of the uterus and you should see a doctor.
Indications: Nolvadex is a medication used to treat breast cancer and
other cancer that has spread to various parts in the body. It is sometimes used to treat breast cancer in
patients after surgery and radiation to reduce the chances of breast cancer in patients considered “high
risk”. The medication is is also used to
prevent complication in women who have had ductal carcinoma in situ (DCIS).
Nolvadex is sometimes prescribed to
treat ovulation problems in women who want to get pregnant but are unable to produce eggs. In addition, the
medication can be used in the treatment of McCune-Albright syndrome, a genetic disease that affects the bones
and color (pigmentation) of the skin in children.
Dosage: Nolvadex comes as white coated tablet to be taken by
mouth. This medication can be taken with or without food. It is usually taken once or twice a day for 5 years or
as directed by a doctor. If you have been prescribed 20 milligrams, divide the pill or liquid in half and take
twice a day: once in the morning and once in the evening.
If you are taking a liquid form of Nolvadex, use a
special measuring spoon and not a household spoon to ensure you get the correct dosage.
Storage: keep nolvadex tightly closed in the
container it came, out of the reach of
children. Store it at room temperature (15-25
° C), away from heat, light and moisture. Nolvadex and all other drugs should not be used beyond the expiration
date printed on the container.
Overdose: nolvadex overdose can be fatal. The
risk is even higher when the drug is overdosed for a long term. In fact, most chemotherapy drugs overdose,
including nolvadex, can lead to death. Even in the absence of overdose, nolvadex can cause strokes, blood clots
in the lungs, and cancer of the uterus. It is extremely important that you take nolvadex as indicated by your
health care provider or according to the directions on the label.
do your best to take
nolvadex around the same time every day.
In case you forget to
take a dose, take the missed one as soon as you remember it. However, if it is almost time for your next
do not double the next dose to recover the missed one; it can be dangerous. Contact your doctor or wait to go back
to your regular schedule. Misusing nolvadex can cause life threatening
Mechanism of action (MOA): Nolvadex is an antiestrogen; it slows
or stops the multiplication of cancer cells by blocking the hormonal effects of estrogen in the body.
Interactions: Very serious interactions can occur if this drug is used with the following
medications: Anastrozole, letrozole. If you are taking any of these
medications, tell your doctor or pharmacist before starting this medication. Make sure your doctor or pharmacist is aware of all prescriptions and
non-prescriptions you are taking before starting this medication. This includes herbal medicines and especially
any medication that causes “thinning of the blood.” Nolvadex
may also interfere with certain lab tests such as thyroid tests. Make sure laboratory staff and doctors are
aware that you are using this specific medication.
Contraindications: Tell your doctor your
complete medical history prior to taking Nolvadex and tell your
doctor or pharmacist if you are allergic to any medications. This medication is not recommended for pregnant
women or women who plan to become pregnant. Be sure to get a pregnancy test before starting the medication and
use a reliable form of birth control. Consult your doctor before
breastfeeding. It’s not known whether this medicine is passed into breast milk and it could cause potential risk
to an infant.
Side Effects: Novaldex not only attacks cancer cells but also healthy
cells, which often leads to development of the following side effects: include:
If the side
effects above persist for weeks, contact your oncologist. In addition, you need to see a health care provider as
soon as you can if you experience any of these symptoms:
1 - encyclopedia.com, document
2 - nlm.nih.gov, Nolvadex