:If you believe you have taken an overdose of this medication, you should call emergency medical help, such as your
nearest poison control station. You may experience some of these symptoms if you have overdosed: irregular
heartbeat, shaking, fainting, and unsteadiness when walking.
Tamoxifen may produce many serious side effects that you should be aware in case you experience any of them. It may
cause allergic reactions, so if you experience any dizziness, trouble breathing, swelling, itching, or rashes, you
should contact your doctor or other medical assistance. You should also seek emergency help immediately if you have
a sudden vision change, confusion, slurred speech, weakness on one side of your body, or chest pain. These side
effects can be caused by a stroke which may be very severe while taking this medication.
While some side effects are more harmful than others, you should be aware of any changes in your body. If you are a
woman, also be aware of any changes in your menstrual cycle or pain in your abdominal area. Always contact your
doctor about side effects you experience during treatment.
This medication is developed to treat cases of breast cancer in both female and male patients. If your cancer has
spread to other parts of the body or if you have recently undergone surgery or radiation your physician may
recommend Tamoxifen. This drug helps to slow or stop the growth of harmful cancer cells in the breast by targeting
Tamoxifen is sometimes prescribed to
treat ovulation problems in women who want to get pregnant but are unable to produce eggs. In addition, the
medication can be used in the treatment of McCune-Albright syndrome, a genetic disease that affects the bones
and color (pigmentation) of the skin in children.
Tamoxifen comes as white coated tablet to
be taken by mouth.
This medication is typically taken orally, either by a pill or a liquid. Follow your doctor’s instructions exactly
to take the accurate dose every day, and at the correct time of day. Each patient may have a different response to
the drug and so your dose instructions may be unique to you.
Tamoxifen overdose can
be fatal. The risk is even higher when the drug is overdosed for a long term. In fact, most chemotherapy
drugs overdose, including Tamoxifen, can lead to death. Even in the absence of overdose, Tamoxifen can cause
strokes, blood clots in the lungs, and cancer of the uterus. It is extremely important that you take
Tamoxifen as indicated by your health care provider or according to the directions on the
your best to take Tamoxifen around the same time every day.
In case you forget to take a dose, take the missed
one as soon as you remember it. However, if it is almost time for your next dose,
do not double the next dose to recover the missed one; it can be dangerous. Contact your doctor or wait to go back
to your regular schedule. Misusing Tamoxifen can cause life threatening
Storage: keep Tamoxifen tightly closed in the
container it came, out of the reach of
children. Store it at room temperature (15-25 °
C), away from heat, light and moisture. Tamoxifen and all other drugs should not be used beyond the expiration date
printed on the container.
: If you are a woman who could become pregnant this medication should not be taken at the same time. For both men
and women receiving this medicine, your doctor will give you two other forms of birth control that are
non-hormonal. This drug can affect unborn babies and it is also not recommended while
the therapy, it is important that you keep all appointments with your doctor and laboratory for regular
medical examinations, especially cardiologic and gynecologic exams. Regular checkups help your physician to
detect early signs of cancer of the uterus or/and heart problems related to Tamoxifen.
Mechanism of action (MOA): Tamoxifen is an antiestrogen; it slows
or stops the multiplication of cancer cells by blocking the hormonal effects of estrogen in the body.
: If your physician is recommending Tamoxifen for your medical condition then there is a good chance that you are
already taking one or more medications. Your doctor will likely monitor all of your medications to make sure that
they are safe to be taking simultaneously. Some medications when taken at the same time can interact with each
other, causing harmful side effects and decreasing the positive effects of the drug. Some drug interactions to watch for include any blood thinners, hormonal forms of
birth controls such as “the pill”, estrogens, plus others. Tell your doctor of any and all other medications you
Side effects: The
medication not The
medication attacks both cancer cells and healthy cells, which
often leads to adverse reactions in most patients. Common Tamoxifen side
If the side
effects above persist for weeks, contact your oncologist. In addition, contact your doctor immediately if you
experience any of these symptoms:
of the skin or eyes
bruising or bleeding
- mouth sores
of the eyes, face, lips, tongue, throat, hands, arms, feet, ankles, or lower legs.
1 - encyclopedia.com, document
2 - nlm.nih.gov, Tamoxifen