Warning: There have been several warnings issued with regards to this
particular medication. One of the most severe possibilities is the significant decrease of white blood cells. When
white blood cells are too low, the body is more susceptible to infection and is not fully able to fight infection
as it normally would. Throughout Taxol treatment, it is standard for doctors to test the white blood cell count
frequently. If the count drops below a safe amount, the administration of this medication should be interrupted.
Contact your doctor immediately if you experience any signs of infection during your treatment, including a fever,
chills, persistent cough or sore throat, or painful, difficult, or frequent urination.
it is uncommon, this medication can cause a severe allergic reaction. If you are allergic to this drug, you
should not receive it again. Seek immediate medical attention if you experience any symptoms of an allergic
reaction in connection with the use of this medication. These symptoms may be swelling, itching, a rash,
dizziness, shortness of breath, or chest pain, among other things.
This is an injectable medication that is used during chemotherapy and whose purpose is to slow or stop the growth
of cancer cells. It can be used alone or along with other medications, as prescribed by a physician. Taxol is a
name brand of the drug paclitaxel. While it is most commonly used to treat breast cancer that has not responded to
treatment or that has come back after treatment, this medication can also be used to treat various other types of
cancer, such as ovarian cancer, lung cancer, cancer of the head or neck, endometrial cancer, cervical cancer,
bladder cancer, cancer of the esophagus, or Kaposi’s sarcoma, among others.
As with other types of
chemotherapy medications, Taxol is to be administered intraveneously under the supervision of a doctor who is
licensed and experienced in the treatment of cancer through chemotherapy.
generally given once every two to three weeks, depending on the type and severity of the cancer.
Contraindications: This medication should not be used if you have
a low white blood cell count.
Taxol or is not recommended under the following
Mechanism of action (MOA): Taxol belongs to antineoplastics, a
class of chemotherapy drugs that works by stabilizing the mitotic spindle (also called nuclear spindle, formation of protein fibers in the cytoplasm of a cell during cell
division), which slows or stops the growth of cancer cells.
Interactions: Taxol has several interactions with other
medications including: medicines that affect the production of white blood cells (for example azathioprine and
trimethoprim), medicines that affect the way that medicines are removed from the body (such as azole antifungals
and some anti-seizure medications). Because this medicine can affect the way that the liver functions, it also
may affect the way that these medications work. Make sure to notify your doctor of all medications that you
take, especially those containing drugs that may cause drowsiness.
Tell your doctor or pharmacist if you are taking any of these medications:
In addition to attacking cancer cells, Taxol may interfere with certain normal cells, causing a number of side
effects in most patients:
- hair loss
loss of appetite
nail or/and skin discoloration
tingling in the hands or toes
If the side
effects above persist for weeks, contact your oncologist. In addition, contact your doctor if you experience any
of these symptoms:
diarrhea or constipation
bruising or bleeding
redness, or swelling at the injection site
signs: skin rash, fever, chills, cough, sore throat, etc.