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Vaginal Cancer Risk Factors 

Many factors are suspected in the development of vaginal cancer; the most common include: 

  • smoking 
  • multiple sexual partners (the fact that it increases your risk of STDs) 
  • history of cervical cancer 
  • having had a hysterectomy 
  • having had radiation therapy to the pelvic area 
  • Age – squamous cell vaginal canceris more common in women aged 50 or over 
  • history of human papillomavirus (HPV) disease such as genital warts 
  • certain precancerous conditions in vagina such as vaginal intraepithelial neoplasia (VAIN) 
  • having taken diethylstilbestrol (DES) during pregnancy 
  • Personal history of gynecologic cancer, especially cervical cancer.  

 

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