Carac (Fluorouracil Cream)

Warning: This medication should not be used during pregnancy. Although very little of the medication is absorbed through normal skin, skin lesions allow the absorption of approximately 20% into the blood stream. This absorption can cause complications with the unborn baby. Before beginning Cara c, talk to your doctor about reliable contraceptives or birth control options. If you believe that you may be pregnant or know that you have become pregnant, inform your doctor immediately. It is unknown whether this medication passes through to breast milk; therefore it is not advisable that you use it during the time that you are nursing.

Also, this medication is known to cause skin to become more sensitive to the sun. Although it is not necessary to completely eliminate sun exposure, it is important to take proper precautions by wearing protective clothing and sunscreen with a minimum SPF of 15. Carac can also cause prolonged hypo-pigmentation or lightening of the skin.

Indications: As a medication that falls under the class of anti-metabolites, this drug has been developed in order to slow the rapid reproduction of skin cells. This is done by preventing the formation of RNA and therefore the creation of DNA, inhibiting the multiplication of new cells.

Carac is one of the brand names for a drug called fluorouracil, a cream that used topically on the skin. Commonly, this medication is prescribed for various precancerous conditions including Bowen’s disease, actinic keratosis, and various other conditions that could be precursors to a more serious skin cancer condition. Not only does it stop these skin cells from reproducing at an unsafe rate, it can also kill existing cells. This medicine is also prescribed for various types of skin cancer.

Dosage: Generally, fluorouracil is to be used once or twice per day. As with all medications, it is important that you follow the instructions of your doctor without decreasing or increasing the dosage unless the change has been specifically approved. Before applying this medication, make sure to cleanse and dry the affected area thoroughly. Then, use your fingertips to gently apply the cream over the entire affected area. As soon as you have completed the application, wash your hands.

Generally, after the use of this medication has begun, patients notice that the affected area becomes somewhat unsightly. This can last for up to several weeks and is considered to be normal and acceptable.

Missing dose: It is important to apply the medication on time exactly as indicated by your physician or pharmacist; in case you forgot to apply the medication, apply the missed dose as soon as you remember it; if it is almost time for the next dose, skip the missed dose and continue your regular dosing. Double dose is not recommended.

Storage: Store Carac at room temperature and out of reach of children. The drug should not be kept in the light or moisture. After use, do not throw the container in the garbage. For more information on proper disposal of Carac, talk to your physician or pharmacist.

Contraindications: It is important to notify your doctor if you have dihydropyrimidine dehydrogenase (DPD) enzyme deficiency before you take this medication Carac because it is considered to be a contraindicator.

While you are treated with Carac, you need to take the following precautions:

  • avoid the treated area to prolonged sun exposure
  • tell your doctor if you have a history of other skin problems or acne rosacea
  • Tell your physician if you are taking prescription or nonprescription medications including aspiring, vitamins and nutritional supplements.

Interactions : Carac is not recommended or should be used with precaution in the following conditions:

  • allergy to fluorouracil or any of its components
  • Pregnancy
  • Breastfeeding
  • Carac can be applied to the skin of infants and children, but under the strict supervision of a physician.

Side effects: Carac can cause skin reactions in some cancer patients. Common Carac side effects include:

  • rash
  • soreness
  • burning
  • crusting
  • redness
  • discoloration
  • irritation
  • Itching

If the side effects above persist for days or weeks, contact your oncologist or your dermatologist so that you can be prescribed an appropriate chemotherapy skin care. In addition, contact your doctor immediately if you experience any of these symptoms:

  • fever
  • chills
  • vomiting
  • bloody diarrhea
  • severe red skin rash
  • Severe stomach pain.

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