Emcyt (Estramustine )

Warning: Emcyt comes in capsule form; certain patients may tend to overdose it. Overdosing the medication could cause serious health problems ranging from small allergic reactions to major deterioration in general health.   Although rare, this medication has caused heart issues. If you notice that you’re experiencing severe, quick changes in your mood, swelling of your hands and/or feet, and an increase in your levels of thirst and urination, it’s recommended that you immediately contact your health care professional.

Indications:  Emcyt is a pill that is recommended in the treatment of certain types of prostate cancer. This medicine must be ingested on a regular basis in order to capitalize on its usage. Users are recommended to make a medication schedule in order to optimize the effectiveness of the medicine.

Emcyt can be prescribed for other medical conditions not mentioned in this article; for more information on diseases for which Emcyt is used to treat, talk to your doctor or pharmacist.

Dosage: Health care professionals will typically prescribe Emcyt to be taken multiple times a day (usually 3-4 times daily, but on occasion a different dosage will be recommended by some health care professionals depending on the specifics of the situation). It is advised that the pills are taken on an empty stomach, either an hour before, or two hours following, a meal. It’s suggested to be taken with a tall glass of water. The amount of time that an individual will need to be on this medication will depend on the specifics of their condition, as well as how well his or her body reacts to the medication and any other treatments that may be administered.

Storage:  store Emcyt at room temperature (15-25 ° C), away from light, moisture and heat above 40 ° C. Emcyt and all other medications should not be used beyond the expiration date printed on the container.  Emcyt should be kept in the container it came in, tightly closed, and out of reach of children.

Overdose:  As with any drug, Emcyt overdose can be dangerous if it is high and taken for long term. An overdose of Emcyt can lead to a life threatening decrease in white blood cells or platelets. If you take an overdose, contact your doctor or a poison control center near you to prevent complications.

Missing dose: In case you missed taking the medication, take it as soon as you remember it if it is not almost time for the next dose. In case it is time or almost time for the next dose, do not double it to recover the missing; it can be dangerous. Contact your doctor or wait to go back to your regular schedule. Continue the treatment even if you feel well. Do not stop taking the drug without first talking to your doctor.

Contraindications: This medication cannot be used by tobacco users, as combining it with tobacco (smokeless and otherwise) will increase the user’s chances of having a stroke, blood clotting, and other complications.

Emcyt is contraindicated for the following groups of people:

  • pregnant women
  • women who are breastfeeding
  • patients allergic to Emcyt or any of its ingredients
  • patients allergic to estrogen and nitrogen mustard
  • patients having a heart condition
  • patients having severe liver disorder
  • Patients who have blood coagulation disorder.

Mechanism of action (MOA):  Emcyt is an anticancer drug classed as an antimicrotubule agent; it destroys cancer cells by inhibiting their growth and multiplication.

Interactions: As would be recommended with any other medication, it is advised that potential users of this medication let their health care professional know about any other medicines they are currently using. The health care professional will oversee the patient’s condition to make sure that the usage of Emcyt will be a good way to treat the user’s condition.

Tell your oncologist if you are taking vitamin supplements. In addition, tell your doctor if you have or have ever had a blood clot, diabetes, high blood pressure, stroke, congestive heart disease, migraines or seizures.

Side Effects: Possible adverse reactions that have been reported as side effects in the usage of Emcyt include vomiting, skin drying and flushing, leg cramps, and erectile dysfunction(decreased sexual desire). These are typically (relatively) mild side effects, and it’s important to remember that, if your doctor has prescribed this medication for you, he or she has determined that the positive effects it will have on your condition will outweigh any of the negatively derived from the side effects. If it seems that any of these side effects are unusually intense, it’s advised that you talk to your health care professional as quickly as possible. In very rare instances, this medication has caused heart issues. If you notice that you’re experiencing severe, quick changes in your mood, swelling of your hands and/or feet, and an increase in your levels of thirst and urination, it’s recommended that you immediately contact your health care professional. This medication may also have an effect on your body’s ability to fight infections. Therefore, it’s advised that, should you develop a prolonged sore throat, chills, or high fevers, that you contact your health care professional immediately.

Other Emcyt adverse effects include:

  • diarrhea
  • constipation
  • leg cramps
  • skin rashes
  • sleep disturbances
  • unusual weakness
  • sensitivity or increase in breast size
  • Reduced interest in sexual activity.

Contact your health care provider immediately if you experience any of these symptoms:

  • fever or chills
  • swelling of feet or lower legs
  • tarry stool (Melena)
  • blood in urine or stools
  • pain in lower back or sides
  • painful or difficult urination
  • pain in chest, groin or legs
  • presence of red spots on the skin
  • persistent headache
  • severe or sudden loss of coordination
  • sudden shortness of breath
  • slurred speech
  • severe depression symptoms
  • unusual bleeding or bruising
  • sudden change in vision
  • Weakness or insensibilization in the arms or legs
  • Persistent cough associated with hoarseness



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