Incidence of esophageal cancer varies geographically. In countries of North America such as the United States, esophageal cancer is uncommon; it represents about 1.8% of adult cancers. While in some other parts of the world such as North China, South Africa, and North-eastern Iran, esophageal cancer occupies an important position among malignant tumors.
According to the National Cancer institute, an estimate of 16.470 esophageal cancer cases was reported in the United States in 2009; killing about 14.530 people. Worldwide, esophageal cancer accounts for about 2.2% of cancer deaths.