Cancer cells can spread to other organs – especially the digestive tract, chest, lungs or skin – and cause severe complications. The nature and severity of the complications depend on the location of the lymphoma.
For example, a lymphoma in the chest can cause facial swelling or accumulation of fluid in the lungs (pleural effusion); a lymphoma in the stomach or small intestine can lead to constipation or severe abdominal pain; if the cancer is localized in the groin, it can lead to swollen legs; if the lymphoma is located in the skin, it can cause thickening and dark discoloration of the skin.